ras oncogene การใช้

• Mannose 6-phosphate receptors ( MPRs ) deliver RAS oncogene family.
• One of the first oncogenes to be defined in cancer research is the ras oncogene.
• This proto-oncogene is a Kirsten ras oncogene homolog from the mammalian ras gene family.
• He led the groups that isolated the ras oncogene, the first known human cancer-causing gene.
• The RAB7A gene belongs to the RAB family of genes, which is a member of the RAS oncogene family.
• Mutant ras oncogenes are found in as many as one-third of all human cancers, including 50 percent of colon cancers, 90 percent of pancreatic cancers and 25 percent of lung cancers.
• Finally, Ras oncogenes can be activated by point mutations so that the GTPase reaction can no longer be stimulated by GAP & ndash; this increases the half life of active Ras-GTP mutants.
• Her most notable achievement in this area involves ras oncogene . antisense methodology ( a process that inhibits the ability of genes to do their work ) can be used to suppress genes that have become cancerous.